The Last Days of Orwell.

[B]eset by poor health in various manifestations, he had to finish off the novel’s manuscript, which he had then tentatively titled The Last Man in Europe, before his conditions finished him off. ‘I am not pleased with the book but I am not absolutely dissatisfied,’ he wrote his agent of the rough draft. ‘I think it is a good idea but the execution would have been better if I had not written it under the influence of TB.'”

In The Guardian, Robert McCrum tells of a desperately sick George Orwell’s race against time to finish 1984. “In late October 1947, oppressed with ‘wretched health’, Orwell recognised that his novel was still ‘a most dreadful mess and about two-thirds of it will have to be retyped entirely’.” Orwell died in January 1950. (As seen as OpenCulture, who also point the way to these jpgs of Orwell’s original manuscript.)