Better Living Through Nanotech.

“A team of chemists and engineers accomplished the feat by inserting tiny synthetic motors inside living cells, moving them around with ultrasonic waves and steering them magnetically. Clearly, it’s not as elegant as the self-propelled, self-guided nanobots envisaged by futurists and scifi, but it’s an important first step. These same basic principles could conceivably be refined and upgraded.”

A glimpse of the future: A Penn State team manage to insert synthetic nanomotors into living cells for the first time. “We might be able to use nanomotors to treat cancer and other diseases by mechanically manipulating cells from the inside. Nanomotors could perform intracellular surgery and deliver drugs noninvasively to living tissues.”

The Morality of the Tribe.

“[I]f you’re like the average American, here’s a fact you don’t know: in 1953, the United States sponsored a coup in Iran, overthrowing a democratically elected government and installing a brutally repressive regime that ruled for decades. Iranians, on the other hand, are very aware of this, which helps explain why, to this day, many of them are gravely suspicious of American intentions…This is the way the brain works: you forget your sins (or never recognize them in the first place) and remember your grievances.”

In a long piece at The Atlantic, Robert Wright ponders recent arguments about the biological basis of morality. “If Greene thinks that getting people to couch their moral arguments in a highly reasonable language will make them highly reasonable, I think he’s underestimating the cleverness and ruthlessness with which our inner animals pursue natural selection’s agenda. We seem designed to twist moral discourse — whatever language it’s framed in — to selfish or tribal ends, and to remain conveniently unaware of the twisting.”

Of Mice and Memory.

“‘Prof Roger Morris, from King’s College London, said: “This finding, I suspect, will be judged by history as a turning point in the search for medicines to control and prevent Alzheimer’s disease.’ He told the BBC a cure for Alzheimer’s was not imminent but: I’m very excited, it’s the first proof in any living animal that you can delay neurodegeneration. The world won’t change tomorrow, but this is a landmark study.'”

Some good news for a change, by way of Dangerous Meta: Scientists have developed (for mice, at least) what appears to be a breakthrough drug that could prevent Alzheimers and other neurodegenerative diseases like Parkinson’s(!):

“When a virus hijacks a brain cell it leads to a build-up of viral proteins. Cells respond by shutting down nearly all protein production in order to halt the virus’s spread. However, many neurodegenerative diseases involve the production of faulty or ‘misfolded’ proteins. These activate the same defences, but with more severe consequences…The researchers used a compound which prevented those defence mechanisms kicking in and in turn halted neurodegeneration.”

We…learn. We…feed.

“‘Slime mould’s remarkable problem-solving capabilities are well-documented and include finding the shortest path between different food sources. It also displays memory, in a similar way to a novel electrical component called a memristor, which has in turn been likened to the functionality of biological brains. ‘It’s one of the simplest organisms that can learn,’ says Gale.”

And now, IT HAS A FACE. Scientists program an old-timey robot to dramatize the electrical signals emanating from slime mold. In a 100,000 years, this is going to seem like one of those Skynet-level bad ideas. And the hat is particularly creepy touch — Very Something Wicked This Way Comes.

Sleep: Nature’s Reset Button.

“More than 20 years ago…we began to suspect that the brain’s activity during slumber may somehow restore to a baseline state the billions of neural connections that get modified every day by the events of waking life. Sleep, in this telling, would preserve the ability of the brain’s circuitry to form new memories continually over the course of an individual’s lifetime without becoming oversaturated or obliterating older memories.”

More Science of Sleep: In Scientific American, two Italian academics put forward their “synaptic homeostasis hypothesis” (SHY) of slumber, whereby the brain weakens (not strengthens, as is usually assumed) synaptic links overnight. “In principle, SHY explains the essential, universal purpose of sleep…sleep restores the brain to a state where it can learn and adapt when we are awake…Most generally, sleep is the price we pay for the brain’s plasticity — its ability to modify its wiring in response to experience.”

Also part of SHY: the idea of “local sleep”: “Recently we have even found that prolonged or intense use of certain circuits can make local groups of neurons ‘fall asleep’ even though the rest of the brain (and the organism itself) remains awake…It seems that when we have been awake for too long or have overexerted certain circuits, small chunks of the brain may take quick naps without giving notice.” I believe in Internet parlance this is known as “haz-ing the dumb.”

Good News, Coffee Achievers.

“In one large-scale epidemiological study from last year, researchers primarily at the National Cancer Institute parsed health information from more than 400,000 volunteers, ages 50 to 71, who were free of major diseases at the study’s start in 1995…men who reported drinking two or three cups of coffee a day were 10 percent less likely to have died than those who didn’t drink coffee, while women drinking the same amount had 13 percent less risk of dying during the study.”

Better living through chemistry: The NYT’s Gretchen Reynolds touts the potential medical benefits of caffeine addiction. “Participants with little or no caffeine circulating in their bloodstreams were far more likely to have progressed to full-blown Alzheimer’s than those whose blood indicated they’d had about three cups’ worth of caffeine.” Factor in all the taurine I consume to boot, and I’m disco.

Seven Minutes of Fury.

“In 12 exercises deploying only body weight, a chair and a wall, it fulfills the latest mandates for high-intensity effort…into about seven minutes of steady discomfort — all of it based on science.”

To complement Calvinism: The NYT lays out a seven-minute workout that might actually work. “The exercises should be performed in rapid succession, allowing 30 seconds for each, while, throughout, the intensity hovers at about an 8 on a discomfort scale of 1 to 10…Those seven minutes should be, in a word, unpleasant.”

The Pleasures of the Void.

“I slid the blackout door closed behind me, eased down into the water, and touched a button that switched off the lights. I was floating in total darkness and silence…For what must have been the first 15 minutes, I wondered what I was doing there…Then a transformation began…My brain went a little haywire. When the storm passed, I found myself in a new and unfamiliar state of mind.”

To kick off his new Slate column “Anything Once,” friend Seth Stevenson finds himself reveling in the sensation of sensory deprivation. “I emerged in a profound daze. I spoke slowly and quietly, like a smooth-jazz DJ, to the person at the spa desk who inquired how my session had gone. I felt more rested than if I’d slept for 16 hours on a pile of tranquilized chinchillas. Outside, colors were saturated; sounds were vivid. I had to try this again, as soon as possible.”

Follow the Bouncing Dot.

“‘We are trying to understand how human motor performance changes with age,’ the researchers say. ‘We believe that research should be done in collaboration with people—with people like you who are interested in learning about themselves and helping research.'”

An online Harvard experiment tries to guess your age by evaluating your mouse-clicking ability. Hard to say how good it is, really. It deemed me thirty — eight years too young — but then again, with blogging and gaming both ranking high among the extra-curriculars, I probably use a mouse more than most people too.

The Expanding Nation.

“This shows the percentages of the U.S. population medically defined as obese, which means a body mass index of 30 or greater…By now everyone knows obesity is a serious issue, but it always helps me to see things moving and in color, and makes the ‘epidemic’ terminology make sense.“

A troubling GIF captures twenty-five years of expanding waistlines in America. “Meanwhile, through 2012, no state has met the CDC’s nationwide goal to reduce obesity to 15 percent.” Update: The states behind the curve? Everyone could be lying.